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When combined with appropriate testosterone optimization, IGF-1 can amplify the benefits of both therapies

15,18 These epigenetic alterations lead to metabolic dysregulation, cartilage degradation, and joint dysfunction (Figure 1)

Oral forms (capsules or sprays) are easier to give but have less predictable absorption

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In a transected Achilles tendon model in rats, the Sikiric group reported dose-dependent improvement in functional recovery, biomechanical strength, and histological healing markers compared with saline-treated controls [Sikiric et al., Inflammopharmacology, 2018]

Controlling the manufacture of telomerase, an enzyme that helps maintain and elongate telomeresthe protective caps on the ends of chromosomesis the aim of Epithalon, which was developed to mimic the effects of Epithalamin